Tech & Science This Pen Can Diagnose Cancer in 10 Seconds

10:26  08 september  2017
10:26  08 september  2017 Source:   Time

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When it comes to treating cancer , surgeons want to get rid of as much cancerous tissue as possible during tumor removal. Now a new technology—the size of a pen —is attempting to make that easier by distinguishing between tumors and healthy tissue in just 10 seconds .

A handheld device that looks like a pen can identify a cancer tissue within 10 seconds and it could be a safer, quicker and precise way of removing a tumour The MasSpec pen is the latest attempt to improve the accuracy of surgery though. Kulsoom Nawaz diagnosed with throat cancer : report.

The MasSpec Pen is a handheld probe that can non-destructively analyze human tissue samples to identify cancer.© Vivian Abagiu/Univ. of Texas at Austin The MasSpec Pen is a handheld probe that can non-destructively analyze human tissue samples to identify cancer. When it comes to treating cancer, surgeons want to get rid of as much cancerous tissue as possible during tumor removal. Now a new technology—the size of a pen—is attempting to make that easier by distinguishing between tumors and healthy tissue in just 10 seconds.

The MasSpec Pen is a real-time diagnostic tool created by researchers at the University of Texas at Austin. In a new study published Wednesday in the journal Science Translational Medicine, the researchers report that their handheld device (which is not yet FDA-approved) uses tiny droplets of water to analyze human tissue samples for cancer with 96% accuracy.

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Hate to be the guy they test this on. "Yes it works!! Oh and sir you have cancer ". Embed Tweet. Replying to @TIME. 10 seconds !

It’s a pen -like tool that can identify cancer tissue in as little as 10 seconds . The tool, which its inventors have named the MasSpec Pen , doesn’t scan a patient for cancer , but rather identifies cancerous tissue by touch.

“It’s a gentle, simple chemical process,” says study author Livia Schiavinato Eberlin, an assistant professor of chemistry at UT Austin. “It’s highly specific and highly sensitive. The fact that it’s non-destructive brings a new approach to cancer diagnosis.”

Getting rid of all cancerous tissue while also preventing any harm to healthy tissue is a delicate process. When operating on a woman with breast cancer, for example, a doctor needs to remove the tumor and other affected tissues while maintaining the rest of the breast. Currently there are other tools available to surgeons for tissue diagnosis, but many use gases or solvents that can be harmful for the human body. In 2016, researchers in Massachusetts reported that they developed a probe that can find and light up cancer cells, making them easier for surgeons to see. But other methods currently available to surgeons today are slower than the MasSpec Pen, the study authors say, in some cases by 30 minutes or more.

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However, the MasSpec Pen took about 10 seconds to provide a diagnosis and was more than 96 percent accurate when tested on tissues removed from 253 human cancer patients. The team has also demonstrated that it accurately diagnoses cancer in live, tumor-bearing mice during surgery

Human cells produce a variety of small molecules, and cancer creates a unique set of them that can be used for pattern identification. The MasSpec Pen produces a small drop of water that extracts molecules from a person’s cells during surgery. Through machine learning, the MasSpec Pen is able to determine what molecular fingerprint is normal and what is cancer, Eberlin says.

In the study, the researchers tested 253 human tissue samples from lung, ovary, thyroid and breast cancer tumors and compared them to samples of healthy tissues. The device was 96% accurate at identifying cancerous tissues. The researchers also tested the MasSpec Pen in live mice with tumors and found that the device was able to identify the presence of cancer without harming healthy surrounding tissues. The device can also identify different subtypes of lung and thyroid cancer, and the team hopes to make it more specified for other types of cancer, too.

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The MasSpec Pen is a simple handheld device that could reduce tissue analysis times from 30 minutes to a mere 10 seconds without harming The MasSpec Pen is a new non-destructive tool that could be used during surgery to identify cancerous tissue in real-time. |

This pen can diagnose cancer in 10 seconds . Unlike other real-time diagnostic tools, this device can distinguish between cancerous and non- cancerous tissue in seconds without harmful side effects, its makers say.

The researchers say they need to continue validating their work and that they plan to start clinical testing in humans in 2018. Until then, it’s unclear how exactly the device will work when integrated into surgery. While the pen-sized device that the surgeon would use is small, the device is connected to a large mass spectrometer, which helps the process of analyzing individual molecules. That large machine would need to be wheeled in and out of a surgery room for each procedure. The pen is disposable, so surgeons would replace it with each surgery.

“This is a good example of a tool that empowers our transition to precision medicine where the treatment can be done with much higher levels of confidence,” says study author Thomas Milner, professor of biomedical engineering in UT Austin’s Cockrell School of Engineering. “Treatment can be planned and given where the outcomes are known. This is one tool along that path.”

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